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Src kinase up-regulates the ERK cascade through inactivation of protein phosphatase 2A following cerebral ischemia
BACKGROUND: The regulation of protein phosphorylation requires a balance in the activity of protein kinases and protein phosphatases. Our previous data indicates that Src can increase ERK activity through Raf kinase in response to ischemic stimuli. This study examined the molecular mechanisms by whi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2714518/ https://ncbi.nlm.nih.gov/pubmed/19602257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-10-74 |
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