Extreme variability in the formation of chlorpyrifos oxon (CPO) in patients poisoned by chlorpyrifos (CPF)

Chlorpyrifos (CPF) is a pesticide that causes tens of thousands of deaths per year worldwide. Chlorpyrifos oxon (CPO) is the active metabolite of CPF that inhibits acetylcholinesterase. However, this presumed metabolite has escaped detection in human samples by conventional methods (HPLC, GC-MS, LC-...

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Главные авторы: Eyer, Florian, Roberts, Darren M., Buckley, Nicholas A., Eddleston, Michael, Thiermann, Horst, Worek, Franz, Eyer, Peter
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier Science 2009
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714474/
https://ncbi.nlm.nih.gov/pubmed/19433070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2009.05.004
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