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Extreme variability in the formation of chlorpyrifos oxon (CPO) in patients poisoned by chlorpyrifos (CPF)

Chlorpyrifos (CPF) is a pesticide that causes tens of thousands of deaths per year worldwide. Chlorpyrifos oxon (CPO) is the active metabolite of CPF that inhibits acetylcholinesterase. However, this presumed metabolite has escaped detection in human samples by conventional methods (HPLC, GC-MS, LC-...

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Detalhes bibliográficos
Main Authors: Eyer, Florian, Roberts, Darren M., Buckley, Nicholas A., Eddleston, Michael, Thiermann, Horst, Worek, Franz, Eyer, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714474/
https://ncbi.nlm.nih.gov/pubmed/19433070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2009.05.004
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