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The Del1 deposition domain can immobilize 3α-hydroxysteroid dehydrogenase in the extracellular matrix without interfering with enzymatic activity

Developing methods that result in targeting of therapeutic molecules in gene therapies to target tissues has importance, as targeting can increase efficacy and decrease off target-side-effects. Work from my laboratory previously showed that the extracellular matrix protein Del1 is organized in the e...

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Detalhes bibliográficos
Main Authors: Hidai, Chiaki, Kitano, Hisataka, Kokubun, Shinichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714445/
https://ncbi.nlm.nih.gov/pubmed/19018576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00449-008-0278-5
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