Enzymatic Transformation of Morphine by Hydroxysteroid Dehydrogenase from Pseudomonas testosteroni

Enzyme preparations from Pseudomonas testosteroni containing α- and β-hydroxysteroid dehydrogenases catalyzed the oxidation of morphine and codeine by nicotinamide adenine dinucleotide. Morphine was converted in relatively low yield into 14-hydroxymorphinone probably via morphinone as an intermediat...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Liras, Paloma, Kasparian, Stephen S., Umbreit, Wayne W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1975
Ämnen:
Metabolism and Products
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC187243/
https://ncbi.nlm.nih.gov/pubmed/172013
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