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Mechanically induced osteogenic differentiation – the role of RhoA, ROCKII and cytoskeletal dynamics

Many biochemical factors regulating progenitor cell differentiation have been examined in detail; however, the role of the local mechanical environment on stem cell fate has only recently been investigated. In this study, we examined whether oscillatory fluid flow, an exogenous mechanical signal wit...

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Hlavní autoři: Arnsdorf, Emily J., Tummala, Padmaja, Kwon, Ronald Y., Jacobs, Christopher R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714434/
https://ncbi.nlm.nih.gov/pubmed/19174467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.036293
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