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Integrins in mammary-stem-cell biology and breast-cancer progression – a role in cancer stem cells?

Cancer cells with stem cell-like properties (cancer stem cells) are believed to drive cancer and are associated with poor prognosis. Data from mouse models have demonstrated that integrins, the major cellular receptors for extracellular-matrix components, have essential roles both during cancer init...

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Autors principals: Pontier, Stephanie M., Muller, William J.
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714417/
https://ncbi.nlm.nih.gov/pubmed/19118213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.040394
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