Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation

The study shows constitutive activation of the Notch pathway in various types of malignancies. However, it remains unclear how the Notch pathway is involved in the pathogenesis of osteosarcoma. We investigated the expression of the Notch pathway molecules in osteosarcoma biopsy specimens and examine...

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Bibliografiske detaljer
Main Authors: Tanaka, M, Setoguchi, T, Hirotsu, M, Gao, H, Sasaki, H, Matsunoshita, Y, Komiya, S
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2009
Fag:
Molecular Diagnostics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714252/
https://ncbi.nlm.nih.gov/pubmed/19455146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605060
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