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Inhibition of Notch pathway prevents osteosarcoma growth by cell cycle regulation

The study shows constitutive activation of the Notch pathway in various types of malignancies. However, it remains unclear how the Notch pathway is involved in the pathogenesis of osteosarcoma. We investigated the expression of the Notch pathway molecules in osteosarcoma biopsy specimens and examine...

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Detalhes bibliográficos
Main Authors: Tanaka, M, Setoguchi, T, Hirotsu, M, Gao, H, Sasaki, H, Matsunoshita, Y, Komiya, S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714252/
https://ncbi.nlm.nih.gov/pubmed/19455146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605060
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