Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-α and matrix metalloproteinase-13 in human chondrocytes

INTRODUCTION: The major risk factor for osteoarthritis (OA) is aging, but the mechanisms underlying this risk are only partly understood. Age-related accumulation of advanced glycation end products (AGEs) can activate chondrocytes and induce the production of proinflammatory cytokines and matrix met...

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Autori principali: Rasheed, Zafar, Anbazhagan, Arivarasu N, Akhtar, Nahid, Ramamurthy, Sangeetha, Voss, Frank R, Haqqi, Tariq M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714117/
https://ncbi.nlm.nih.gov/pubmed/19445683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2700
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