Postnatal early overnutrition changes the leptin signalling pathway in the hypothalamic–pituitary–thyroid axis of young and adult rats

Postnatal early overnutrition (EO) is a risk factor for obesity in adult life. Rats raised in a small litter can develop hyperinsulinaemia, hyperphagia, hyperleptinaemia and hypertension as adults. Since leptin regulates the hypothalamic–pituitary–thyroid axis and the metabolism of thyroid hormones,...

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Detalhes bibliográficos
Main Authors: Rodrigues, Ananda Lages, de Moura, Egberto Gaspar, Passos, Magna Cottini Fonseca, Dutra, Sheila Cristina Potente, Lisboa, Patricia Cristina
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Renal and Endocrine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714028/
https://ncbi.nlm.nih.gov/pubmed/19403617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.169045
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