Developmental changes in hypothalamic leptin receptor: relationship with the postnatal leptin surge and energy balance neuropeptides in the postnatal rat

In the adult brain, leptin regulates energy homeostasis primarily via hypothalamic circuitry that affects food intake and energy expenditure. Evidence from rodent models has demonstrated that during early postnatal life, leptin is relatively ineffective in modulating these pathways, despite the high...

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Autori principali: Cottrell, E. C., Cripps, R. L., Duncan, J. S., Barrett, P., Mercer, J. G., Herwig, A., Ozanne, S. E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2009
Soggetti:
Developmental Physiology and Pregnancy
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665846/
https://ncbi.nlm.nih.gov/pubmed/19144754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.90690.2008
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