Uteroplacental insufficiency causes a nephron deficit, modest renal insufficiency but no hypertension with ageing in female rats

In rats, uteroplacental insufficiency induced by uterine vessel ligation restricts fetal growth and impairs mammary development compromising postnatal growth. In male offspring, this results in a nephron deficit and hypertension which can be reversed by improving lactation and postnatal growth. Here...

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Main Authors: Moritz, Karen M, Mazzuca, Marc Q, Siebel, Andrew L, Mibus, Amy, Arena, Debbie, Tare, Marianne, Owens, Julie A, Wlodek, Mary E
Formáid: Artigo
Teanga:Inglês
Foilsithe: Blackwell Science Inc 2009
Ábhair:
Renal and Endocrine
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714027/
https://ncbi.nlm.nih.gov/pubmed/19359373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.170407
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