Uteroplacental insufficiency causes a nephron deficit, modest renal insufficiency but no hypertension with ageing in female rats

In rats, uteroplacental insufficiency induced by uterine vessel ligation restricts fetal growth and impairs mammary development compromising postnatal growth. In male offspring, this results in a nephron deficit and hypertension which can be reversed by improving lactation and postnatal growth. Here...

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Detalhes bibliográficos
Main Authors: Moritz, Karen M, Mazzuca, Marc Q, Siebel, Andrew L, Mibus, Amy, Arena, Debbie, Tare, Marianne, Owens, Julie A, Wlodek, Mary E
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Renal and Endocrine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714027/
https://ncbi.nlm.nih.gov/pubmed/19359373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.170407
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