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Tumour necrosis factor α activates nuclear factor κB signalling to reduce N-type voltage-gated Ca(2+) current in postganglionic sympathetic neurons

Inflammation has profound effects on the innervation of affected tissues, including altered neuronal excitability and neurotransmitter release. As Ca(2+) influx through voltage-gated Ca(2+) channels (VGCCs) is a critical determinant of excitation–secretion coupling in nerve terminals, the aim of thi...

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Hlavní autoři: Motagally, Mohamed A, Lukewich, Mark K, Chisholm, Susan P, Neshat, Shadia, Lomax, Alan E
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714026/
https://ncbi.nlm.nih.gov/pubmed/19403618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.172312
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