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Modulation of Brain Hemichannels and Gap Junction Channels by Pro-Inflammatory Agents and Their Possible Role in Neurodegeneration

In normal brain, neurons, astrocytes, and oligodendrocytes, the most abundant and active cells express pannexins and connexins, protein subunits of two families forming membrane channels. Most available evidence indicates that in mammals endogenously expressed pannexins form only hemichannels and co...

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Autors principals: Orellana, Juan A., Sáez, Pablo J., Shoji, Kenji F., Schalper, Kurt A., Palacios–Prado, Nicolás, Velarde, Victoria, Giaume, Christian, Bennett, Michael V.L., Sáez, Juan C.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713807/
https://ncbi.nlm.nih.gov/pubmed/18816186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2008.2130
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