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Modulation of Brain Hemichannels and Gap Junction Channels by Pro-Inflammatory Agents and Their Possible Role in Neurodegeneration

In normal brain, neurons, astrocytes, and oligodendrocytes, the most abundant and active cells express pannexins and connexins, protein subunits of two families forming membrane channels. Most available evidence indicates that in mammals endogenously expressed pannexins form only hemichannels and co...

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Main Authors: Orellana, Juan A., Sáez, Pablo J., Shoji, Kenji F., Schalper, Kurt A., Palacios–Prado, Nicolás, Velarde, Victoria, Giaume, Christian, Bennett, Michael V.L., Sáez, Juan C.
格式: Artigo
語言:Inglês
出版: Mary Ann Liebert, Inc. 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713807/
https://ncbi.nlm.nih.gov/pubmed/18816186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2008.2130
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