The ADP-stimulated NADPH oxidase activates the ASK-1/MKK4/JNK pathway in alveolar macrophages

The role of H(2)O(2) as a second messenger in signal transduction pathways is well established. We show here that the NADPH oxidase-dependent production of [Formula: see text] and H(2)O(2) or respiratory burst in alveolar macrophages (AM) (NR8383 cells) is required for ADP-stimulated c-Jun phosphory...

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Main Authors: Liu, Honglei, Zhang, Hongqiao, Iles, Karen E., Rinna, Alessandra, Merrill, Gary, Yodoi, Junji, Torres, Martine, Forman, Henry Jay
格式: Artigo
語言:Inglês
出版: 2006
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713795/
https://ncbi.nlm.nih.gov/pubmed/17015265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10715760600758514
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