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The ADP-stimulated NADPH oxidase activates the ASK-1/MKK4/JNK pathway in alveolar macrophages
The role of H(2)O(2) as a second messenger in signal transduction pathways is well established. We show here that the NADPH oxidase-dependent production of [Formula: see text] and H(2)O(2) or respiratory burst in alveolar macrophages (AM) (NR8383 cells) is required for ADP-stimulated c-Jun phosphory...
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| Main Authors: | , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2713795/ https://ncbi.nlm.nih.gov/pubmed/17015265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10715760600758514 |
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