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Structural Insights into Regioselectivity in the Enzymatic Chlorination of Tryptophan

The regioselectively controlled introduction of chlorine into organic molecules is an important biological and chemical process. This importance derives from the observation that many pharmaceutically active natural products contain a chlorine atom. Flavin-dependent halogenases are one of the princi...

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Detalhes bibliográficos
Main Authors: Zhu, Xiaofeng, De Laurentis, Walter, Leang, Khim, Herrmann, Julia, Ihlefeld, Katja, van Pée, Karl-Heinz, Naismith, James H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713781/
https://ncbi.nlm.nih.gov/pubmed/19501593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.06.008
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