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Direct Determination of Kinetic Rates from Single-Molecule Photon Arrival Trajectories Using Hidden Markov Models

The measurement of fluorescence from single protein molecules has become an important new tool in the study of dynamic processes, allowing for the direct visualization of the motions experienced by individual proteins and macromolecular complexes. The data from such single-molecule experiments are i...

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Main Authors: Andrec, Michael, Levy, Ronald M., Talaga, David S.
Formato: Artigo
Idioma:Inglês
Publicado: 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713777/
https://ncbi.nlm.nih.gov/pubmed/19626138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp035514+
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