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Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

To identify risk variants for lung cancer, we conducted a multistage genome-wide association study. In the discovery phase, we analyzed 315,450 tagging SNPs in 1,154 current and former (ever) smoking cases of European ancestry and 1,137 frequency-matched, ever-smoking controls from Houston, Texas. F...

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Hlavní autoři: Amos, Christopher I, Wu, Xifeng, Broderick, Peter, Gorlov, Ivan P, Gu, Jian, Eisen, Timothy, Dong, Qiong, Zhang, Qing, Gu, Xiangjun, Vijayakrishnan, Jayaram, Sullivan, Kate, Matakidou, Athena, Wang, Yufei, Mills, Gordon, Doheny, Kimberly, Tsai, Ya-Yu, Chen, Wei Vivien, Shete, Sanjay, Spitz, Margaret R, Houlston, Richard S
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713680/
https://ncbi.nlm.nih.gov/pubmed/18385676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.109
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