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Chromosome 15q25 (CHRNA3-CHRNA5) Variation Impacts Indirectly on Lung Cancer Risk

Genetic variants at the 15q25 CHRNA5-CHRNA3 locus have been shown to influence lung cancer risk however there is controversy as to whether variants have a direct carcinogenic effect on lung cancer risk or impact indirectly through smoking behavior. We have performed a detailed analysis of the 15q25...

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Autors principals: Wang, Yufei, Broderick, Peter, Matakidou, Athena, Eisen, Timothy, Houlston, Richard S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084737/
https://ncbi.nlm.nih.gov/pubmed/21559498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019085
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