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Chromosome End Maintenance by Telomerase

Telomeres, protein-DNA complexes at the ends of eukaryotic linear chromosomes, are essential for genome stability. The accumulation of chromosomal abnormalities in the absence of proper telomere function is implicated in human aging and cancer. Repetitive telomeric sequences are maintained by telome...

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Autors principals: Osterhage, Jennifer L., Friedman, Katherine L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713563/
https://ncbi.nlm.nih.gov/pubmed/19286666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R900011200
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