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Elucidating Conformational Changes in the γ-Aminobutyric Acid Transporter-1
The GABA transporter-1 (GAT-1) has three current-generating modes: GABA-coupled current, Li(+)-induced leak current, and Na(+)-dependent transient currents. We earlier hypothesized that Li(+) is able to substitute for the first Na(+) in the transport cycle and thereby induce a distinct conformation...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2713550/ https://ncbi.nlm.nih.gov/pubmed/19363027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.003137 |
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