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An Acid-activated Nucleobase Transporter from Leishmania major

Parasitic protozoa are unable to synthesize purines de novo and must import preformed purine nucleobases or nucleosides from their hosts. Leishmania major expresses two purine nucleobase transporters, LmaNT3 and LmaNT4. Previous studies revealed that at neutral pH, LmaNT3 is a broad specificity, hig...

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Bibliografiska uppgifter
Huvudupphovsmän: Ortiz, Diana, Sanchez, Marco A., Koch, Hans P., Larsson, H. Peter, Landfear, Scott M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713545/
https://ncbi.nlm.nih.gov/pubmed/19366701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.006718
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