Identification and Functional Characterization of Protein Kinase A-catalyzed Phosphorylation of Potassium Channel Kv1.2 at Serine 449

Vascular smooth muscle Kv1 delayed rectifier K(+) channels (K(DR)) containing Kv1.2 control membrane potential and thereby regulate contractility. Vasodilatory agonists acting via protein kinase A (PKA) enhance vascule smooth muscle Kv1 activity, but the molecular basis of this regulation is uncerta...

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Detalhes bibliográficos
Main Authors: Johnson, Rosalyn P., El-Yazbi, Ahmed F., Hughes, Morgan F., Schriemer, David C., Walsh, Emma J., Walsh, Michael P., Cole, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713528/
https://ncbi.nlm.nih.gov/pubmed/19389710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.010918
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