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Distinct BRAF (V600E) and KRAS Mutations in High Microsatellite Instability Sporadic Colorectal Cancer in African Americans

PURPOSE: Colorectal cancer develops through genetic, epigenetic, and environmental events that result in uncontrolled cell proliferation. Colorectal cancer incidence and mortality is higher in African Americans (AA) than in the general population. Here, we carried out a molecular analysis of sporadi...

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Detalhes bibliográficos
Main Authors: Kumar, Krishan, Brim, Hassan, Giardiello, Francis, Smoot, Duane T., Nouraie, Mehdi, Lee, Edward L., Ashktorab, Hassan
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713502/
https://ncbi.nlm.nih.gov/pubmed/19190129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-1029
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