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Structure/Function Analysis of PARP-1 in Oxidative and Nitrosative Stress-Induced Monomeric ADPR Formation

Poly adenosine diphosphate-ribose polymerase-1 (PARP-1) is a multifunctional enzyme that is involved in two major cellular responses to oxidative and nitrosative (O/N) stress: detection and response to DNA damage via formation of protein-bound poly adenosine diphosphate-ribose (PAR), and formation o...

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Bibliografiske detaljer
Main Authors: Buelow, Ben, Uzunparmak, Burak, Paddock, Marcia, Scharenberg, Andrew M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713433/
https://ncbi.nlm.nih.gov/pubmed/19641624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006339
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