Preclinical Assessment of the Treatment of Second-Stage African Trypanosomiasis with Cordycepin and Deoxycoformycin

BACKGROUND: There is an urgent need to substitute the highly toxic compounds still in use for treatment of the encephalitic stage of human African trypanosomiasis (HAT). We here assessed the treatment with the doublet cordycepin and the deaminase inhibitor deoxycoformycin for this stage of infection...

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Detalhes bibliográficos
Main Authors: Vodnala, Suman K., Ferella, Marcela, Lundén-Miguel, Hilda, Betha, Evans, van Reet, Nick, Amin, Daniel Ndem, Öberg, Bo, Andersson, Björn, Kristensson, Krister, Wigzell, Hans, Rottenberg, Martin E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713411/
https://ncbi.nlm.nih.gov/pubmed/19652702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000495
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