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Heterochromatinization as a Potential Mechanism of Nickel-Induced Carcinogenesis
Epigenetics refers to heritable patterns of gene expression that do not depend on alterations of the genomic DNA sequence. Nickel compounds have demonstrated carcinogenicity without any associated mutagenesis, suggesting that its mechanism of carcinogenesis is epigenetic in nature. One such potentia...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2713359/ https://ncbi.nlm.nih.gov/pubmed/19338343 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900246h |
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