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Heterochromatinization as a Potential Mechanism of Nickel-Induced Carcinogenesis

Epigenetics refers to heritable patterns of gene expression that do not depend on alterations of the genomic DNA sequence. Nickel compounds have demonstrated carcinogenicity without any associated mutagenesis, suggesting that its mechanism of carcinogenesis is epigenetic in nature. One such potentia...

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Hlavní autoři: Ellen, Thomas P., Kluz, Thomas, Harder, Mark E., Xiong, Judy, Costa, Max
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713359/
https://ncbi.nlm.nih.gov/pubmed/19338343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi900246h
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