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Sensing Chromosome Bi-Orientation By Spatial Separation Of Aurora B Kinase From Kinetochore Substrates
Successful cell division requires that chromosomes attach to opposite poles of the mitotic spindle (bi-orientation). Aurora B kinase regulates chromosome-spindle attachments by phosphorylating kinetochore substrates that bind microtubules. Centromere tension stabilizes bi-oriented attachments, but h...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2713345/ https://ncbi.nlm.nih.gov/pubmed/19150808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1167000 |
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