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Shugoshin-1 Balances Aurora B Kinase Activity via PP2A to Promote Chromosome Bi-orientation

Correction of faulty kinetochore-microtubule attachments is essential for faithful chromosome segregation and dictated by the opposing activities of Aurora B kinase and PP1 and PP2A phosphatases. How kinase and phosphatase activities are appropriately balanced is less clear. Here, we show that a cen...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Meppelink, Amanda, Kabeche, Lilian, Vromans, Martijn J.M., Compton, Duane A., Lens, Susanne M.A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718550/
https://ncbi.nlm.nih.gov/pubmed/25892238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.03.052
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