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Regulatory sequences in the 3’ Untranslated region of the human cGMP-Phosphodiesterase β-Subunit gene

PURPOSE: Rod cGMP-phosphodiesterase, a key enzyme in visual transduction, is important for retinal integrity and function. Mutations in the gene encoding its β-subunit (PDEβ) cause retinal degeneration in animals and humans. Here we tested the hypothesis that elements in the 3’UTR of the PDEβ gene a...

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Detalhes bibliográficos
Main Authors: Verardo, Mark R., Viczian, Andrea, Piri, Natik, Knox, Barry E., Farber, Debora B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713258/
https://ncbi.nlm.nih.gov/pubmed/19218616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2010
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