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Expression of HNF4alpha in the human and rat choroid plexus – Implications for drug transport across the blood-cerebrospinal-fluid (CSF) barrier

BACKGROUND: The choroid plexus consists of highly differentiated epithelium and functions as a barrier at the interface of the blood-cerebrospinal-fluid (CSF). This tissue may therefore determine the bioavailability and transport of drugs to the brain. Little is known about the expression of drug an...

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Autors principals: Niehof, Monika, Borlak, Jürgen
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713241/
https://ncbi.nlm.nih.gov/pubmed/19575803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-10-68
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