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Therapy of Head and Neck Squamous Cell Carcinoma with Replicative Adenovirus Expressing Tissue Inhibitor of Metalloproteinase-2 and Chemoradiation
OBJECTIVE: Recent studies have demonstrated efficacy of targeted therapy combined with radiotherapy in HNSCC. We hypothesized that a combination treatment including a replicating adenovirus armed with tissue inhibitor metalloproteinase-2 (TIMP-2), radiation, and Cisplatin will augment treatment resp...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2713186/ https://ncbi.nlm.nih.gov/pubmed/18846112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2008.76 |
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