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In vivo Efficacy of Marimastat and Chemoradiation in Head and Neck Cancer Xenografts
OBJECTIVE: To assess the effect of combining a synthetic matrix metalloprotease inhibitor and chemoradiation therapy on tumor growth in a murine model of head and neck squamous-cell carcinoma (SCC). METHODS: Athymic, nude mice bearing SCC-1 xenografts were used to comprise 4 treatment groups: (1) co...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
S. Karger AG
2009
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2700630/ https://ncbi.nlm.nih.gov/pubmed/18931526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000163217 |
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