Cyclophosphamide Unmasks an Antimetastatic Effect of Local Tumor Cryoablation

Cryoablation of a solitary tumor mass releases intact tumor antigens and can induce protective antitumor immunity but has limited efficacy in the treatment of established metastatic cancer. Cyclophosphamide (Cy), an anticancer drug, selectively depletes regulatory T cells (T(reg)s) and attenuates su...

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Autors principals: Levy, Moshe Yair, Sidana, Abhinav, Chowdhury, Wasim H., Solomon, Steven B., Drake, Charles G., Rodriguez, Ronald, Fuchs, Ephraim J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Pharmacology and Experimental Therapeutics 2009
Matèries:
Cellular and Molecular
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713091/
https://ncbi.nlm.nih.gov/pubmed/19407102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.152603
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