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Chr 19(A/J) modifies tumor resistance in a sex and parent-of-origin specific manner

Neurofibromatosis type 1 (NF1) is one of the most common human genetic diseases affecting the nervous system and predisposes individuals to cancer, including peripheral nerve sheath tumors (PNSTs) and astrocytomas. Modifiers in the genetic background affect the severity of the disease and we have pr...

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Detalhes bibliográficos
Main Authors: Walrath, Jessica C., Fox, Kristi, Truffer, Erika, Alvord, W. Gregory, Quiñones, Octavio A., Reilly, Karlyne M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2713021/
https://ncbi.nlm.nih.gov/pubmed/19347398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-009-9179-4
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