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Desmoglein 1–dependent suppression of EGFR signaling promotes epidermal differentiation and morphogenesis

Dsg1 (desmoglein 1) is a member of the cadherin family of Ca(2+)-dependent cell adhesion molecules that is first expressed in the epidermis as keratinocytes transit out of the basal layer and becomes concentrated in the uppermost cell layers of this stratified epithelium. In this study, we show that...

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Detalhes bibliográficos
Main Authors: Getsios, Spiro, Simpson, Cory L., Kojima, Shin-ichiro, Harmon, Robert, Sheu, Linda J., Dusek, Rachel L., Cornwell, Mona, Green, Kathleen J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712955/
https://ncbi.nlm.nih.gov/pubmed/19546243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200809044
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