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Tumoricidal Effects of Activated Macrophages in a Mouse Model of Chronic Lymphocytic Leukemia

The Eμ-TCL1 transgenic mouse spontaneously develops a CD5(+) B cell lymphoproliferative disorder similar to human chronic lymphocytic leukemia (CLL). Given the ineffectual T cell antitumor responses in this mouse model of CLL, we sought to determine whether combined treatment with anti-CD40 mAb (αCD...

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Detalhes bibliográficos
Main Authors: Wu, Qing-Li, Buhtoiarov, Ilia N., Sondel, Paul M., Rakhmilevich, Alexander L., Ranheim, Erik A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712940/
https://ncbi.nlm.nih.gov/pubmed/19454672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0801847
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