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DNA Recognition by the Aberrant Retinoic Acid Receptors Implicated in Human Acute Promyelocytic Leukemia

Human acute promyelocytic leukemias (APLs) are associated with chromosomal translocations that replace the NH(2) terminus of wild-type retinoic acid receptor (RAR) α with portions of the promyelocytic leukemia protein (PML) or promyelocytic leukemia zinc-finger protein (PLZF). The wild-type RARα rea...

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Bibliographic Details
Main Authors: Hauksdóttir, Herborg, Privalsky, Martin L.
Format: Artigo
Language:Inglês
Published: 2001
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712924/
https://ncbi.nlm.nih.gov/pubmed/11243468
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