Availability of autoantigenic epitopes controls phenotype, severity, and penetrance in TCR Tg autoimmune gastritis

We examined TCR: MHC/peptide interactions and in vivo epitope availability to explore the Th1- or Th2-like phenotype of autoimmune disease in two TCR Tg mouse models of autoimmune gastritis (AIG). The TCR of strains A23 and A51 recognize distinct IA(d)-restricted peptides from the gastric parietal c...

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Main Authors: Levin, Ditza, DiPaolo, Richard J., Brinster, Carine, Revilleza, Maria Jamela R., Boyd, Lisa F., Teyton, Luc, Natarajan, Kannan, Mage, Michael G., Shevach, Ethan M., Margulies, David H.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712832/
https://ncbi.nlm.nih.gov/pubmed/19039784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838584
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