Unique Hexosaminidase Reduces Metabolic Survival Signal and Sensitizes Cardiac Myocytes to Hypoxia-Reoxygenation Injury

Metabolic signaling through the post-translational linkage of N-acetylglucosamine (O-GlcNAc) to cellular proteins represents a unique signaling paradigm operative during lethal cellular stress, and, a pathway we and others have recently shown to exert cytoprotective effects in vitro and in vivo. Acc...

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Bibliographic Details
Main Authors: Ngoh, Gladys A., Facundo, Heberty T., Hamid, Tariq, Dillmann, Wolfgang, Zachara, Natasha E., Jones, Steven P.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712829/
https://ncbi.nlm.nih.gov/pubmed/19023128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.189431
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