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Unique Hexosaminidase Reduces Metabolic Survival Signal and Sensitizes Cardiac Myocytes to Hypoxia-Reoxygenation Injury
Metabolic signaling through the post-translational linkage of N-acetylglucosamine (O-GlcNAc) to cellular proteins represents a unique signaling paradigm operative during lethal cellular stress, and, a pathway we and others have recently shown to exert cytoprotective effects in vitro and in vivo. Acc...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2712829/ https://ncbi.nlm.nih.gov/pubmed/19023128 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.189431 |
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