Global DNA Hypomethylation (LINE-1) in the Normal Colon and Lifestyle Characteristics, Dietary and Genetic Factors

BACKGROUND: Global loss of methylated cytosines in DNA, thought to predispose to chromosomal instability and aneuploidy, has been associated with an increased risk of colorectal neoplasia. Little is known about the relationships between global hypomethylation and lifestyle, demographics, dietary mea...

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Hauptverfasser: Figueiredo, Jane C., Grau, Maria V., Wallace, Kristin, Levine, A. Joan, Shen, Lanlan, Hamdan, Randala, Chen, Xinli, Bresalier, Robert S., McKeown-Eyssen, Gail, Haile, Robert W., Baron, John A., Issa, Jean-Pierre J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712652/
https://ncbi.nlm.nih.gov/pubmed/19336559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-08-0926
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