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Designing ligands to bind proteins
The ability to design drugs (so-called ‘rational drug design’) has been one of the long-term objectives of chemistry for 50 years. It is an exceptionally difficult problem, and many of its parts lie outside the expertise of chemistry. The much more limited problem – how to design tight-binding ligan...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2712650/ https://ncbi.nlm.nih.gov/pubmed/16817982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/S0033583506004240 |
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