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Phosphodiesterase 1C is dispensable for rapid response termination of olfactory sensory neurons

In the nose, odorants are detected on the cilia of olfactory sensory neurons (OSNs), where a cAMP-mediated signaling pathway transforms odor stimulation into electrical responses. Phosphodiesterase (PDE) activity in OSN cilia was long thought to account for rapid response termination by degrading od...

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Detalhes bibliográficos
Main Authors: Cygnar, Katherine D., Zhao, Haiqing
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712288/
https://ncbi.nlm.nih.gov/pubmed/19305400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2289
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