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Ca(2+)/calmodulin-mediated fast desensitization by the B1b subunit of the CNG channel affects response termination but not sensitivity to recurring stimulation in olfactory sensory neurons
Ca(2+)/calmodulin-mediated negative feedback is a prototypical regulatory mechanism for Ca(2+) permeable ion channels. In olfactory sensory neurons (OSNs) such regulation on the cyclic nucleotide-gated (CNG) channel is considered a major mechanism of OSN adaptation. To determine the role of Ca(2+)/c...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587172/ https://ncbi.nlm.nih.gov/pubmed/18466748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.02.029 |
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