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Tolerance to Sedative/Hypnotic Actions of GABAergic Drugs Correlates With Tolerance to Potentiation of Extrasynaptic Tonic Currents of Alcohol-Dependent Rats
Alcohol tolerance resulting from chronic administration is well known to be accompanied by cross-tolerance to sedative/anesthetic drugs, especially those acting on the γ-aminobutyric acid type A receptors (GABA(A)Rs). Rats treated with chronic intermittent ethanol (CIE) show decreased function and a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Physiological Society
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2712270/ https://ncbi.nlm.nih.gov/pubmed/19420124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.90484.2008 |
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