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Tolerance to Sedative/Hypnotic Actions of GABAergic Drugs Correlates With Tolerance to Potentiation of Extrasynaptic Tonic Currents of Alcohol-Dependent Rats

Alcohol tolerance resulting from chronic administration is well known to be accompanied by cross-tolerance to sedative/anesthetic drugs, especially those acting on the γ-aminobutyric acid type A receptors (GABA(A)Rs). Rats treated with chronic intermittent ethanol (CIE) show decreased function and a...

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Bibliografische gegevens
Hoofdauteurs: Liang, Jing, Spigelman, Igor, Olsen, Richard W.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2712270/
https://ncbi.nlm.nih.gov/pubmed/19420124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.90484.2008
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