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Interleukin-4 suppresses the cytotoxic potential of in vitro generated, adaptive regulatory CD4(+) T cells by down-regulation of granzyme B
Regulatory CD4(+) T cells (Tregs) control immune responses using secretion of anti-inflammatory cytokines and/or cytotoxic mechanisms and play a central role in the outcomes of several immune pathologies. Previous studies suggest an impaired function of Tregs in allergy, especially during allergen s...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2712102/ https://ncbi.nlm.nih.gov/pubmed/19191911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2008.02993.x |
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